The clinical aspects of 'juvenile general paralysis' : with an account of a case treated with '606,' and observations on prophylaxis / by J. Johnston Abraham.

  • Abraham, James Johnston, 1876-1963.
Date:
[1911]
Catalogue details

Licence: In copyright

Credit: The clinical aspects of 'juvenile general paralysis' : with an account of a case treated with '606,' and observations on prophylaxis / by J. Johnston Abraham. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    GENEKAL PAKALYSIS,” WITH AN ACCOUNT OF A CASE TREATED WITH “606,” AND OBSERVATIONS ON PROPHYLAXIS. The history of juvenile general paralysis bears a curious resemblance to that of many other diseases once considered rare, now generally recognised as of comparatively frequent occurrence. Its existence was unknown until 1877, when Clouston published a description (1)' of his first case in a boy, aged 16 years, under the name of “developmental general paralysis,” and showed that it resembled, both clinically and pathologically, the form up to then considered exclusively confined to adult life. Two years later a second case was (described by Turnbull in a child aged 12 years (2), and again two years later similar isolated examples by Nolan and Wigles- worth (3). It was in the same year that Regis recorded the first case on the continent (4). The condition was still considered very rare. Nevertheless, in 1895 Alzheimer had collected 40 cases, including 3 of his own (5), and in 1898 Thiry (6) had raised the number of known cases to 69. In 1900 Mott (7) published an elaborate analysis of 22 cases, collected in three years, from the London County Asylums alone, in 1908 he had raised the number of cases observed by him to 40 (8), and in 1910 to 60 (9). In the last 10 years cases have been recorded with increasing frequency from many other countries, till now there must be several hundreds in the literature, and it is not surprising to find that Fennell (10), as * The parenthetical figures occurring throughout the article refer To the bibliography at the end.