Pharmacokinetics. Part 2, Intravenous dosing and the 2-compartment model.

London : University of London Audio-Visual Centre, 1976.

1 encoded moving image (27.40) : sound, black and white

00:27:40

University of London

Unrestricted

CC-BY-NC

Creative Commons Attribution-Non-Commercial 2.0 UK: England & Wales

In English

Presented by Professor Leonard Saunders, The School of Pharmacy. Produced by David Clark and Michael Tomlinson. Made by University of London Audio-Visual Centre. Made for British Postgraduate Medical Federation.

This video is one of around 310 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and 1980s, thus constituting a contemporary medical-historical archive of great interest. The lectures mostly take place in a small and intimate studio setting and are often face-to-face. The lecturers use a wide variety of resources to illustrate their points, including film clips, slides, graphs, animated diagrams, charts and tables as well as 3-dimensional models and display boards with movable pieces. Some of the lecturers are telegenic while some are clearly less comfortable about being recorded; all are experts in their field and show great enthusiasm to share both the latest research and the historical context of their specialist areas.

Segment 1 Intertitle: 'The Mechanism.' Saunders introduces the lecture standing in front of graphs, animated diagrams and tables of differential equations showing how intravenous drug doses function in a two compartment model. Time start: 00:00:00:00 Time end: 00:06:44:00 Length: 00:06:44:00

Segment 2 Saunders runs through a series of differential equations relating to intravenous drug doses. Time start: 00:06:44:00 Time end: 00:14:07:00 Length: 00:07:23:00

Segment 3 Intertitle: 'Obtaining Kinetic Parameters.' Saunders speaks again about a two compartment model for intravenous drug dosing and refers to many differential equations and a computer programme model of equations. Time start: 00:14:07:00 Time end: 00:21:22:00 Length: 00:07:15:00

Segment 4 Saunders shows computer output data, a table comparing results and then tables showing differential equations. He ends the lecture by saying that the next programme will be about the kinetics after oral dosing. Time start: 00:21:22:00 Time end: 00:27:40:03 Length: 00:06:18:00