Growth hormone receptor, molecular model
- T.Blundell & N Campillo
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Description
Molecular model of growth hormone (GH) and its
receptor (GHR), ribbon diagram, no labels.
Representation of the general architecture of the
2:2 complex (PDB code:1axi). The two receptor
molecules in yellow, the growth hormones in
violet. GH elicits a variety of biological
activities mainly mediated by the GHR.
GH, synthesized in and secreted from the anterior
pituitary lobe has multiple effects on growth,
metabolism and the immune system.