Drug-releasing depots in mouse lungs.

  • Szeto, Gregory.
Date:
2014
  • Digital Images
  • Online

Available online

view Drug-releasing depots in mouse lungs.

Contains: 1 image

Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

You can copy and distribute this work, as long as it is not primarily intended for or directed to commercial advantage or monetary compensation. You should also provide attribution to the original work, source and licence. If you make any modifications to or derivatives of the work, it may not be distributed. Read more about this licence.

Credit

Drug-releasing depots in mouse lungs. Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0). Source: Wellcome Collection.

Selected images from this work

View 1 image

About this work

Description

Confocal micrograph of whole mouse lungs loaded with drug carrying microparticles (red/pink). The microparticles were also loaded with a fluorescent tracking dye so that they could be visualised 1 week after administration. Cell nuclei (blue) and cell membrane sugars (green) are also visible. The right lung in mice is divided into four lobes (right side of image), but the left lung has only one lobe (left side of image). The top of the lungs are orientated towards the top of the image. Remnants of the windpipe (trachea) and surrounding tissue are visible in the centre of the image. Current anti-cancer therapies have many toxic side effects so research into other ways of delivering drugs to specific areas of the body are being investigated in order to decrease these unwanted side effects. Here, microparticles were delivered to the lungs using a route similar to drugs administered by an inhaler. Horizontal width of image is 12.7 mm. Confocal micrograph 2014

Publication/Creation

2014.

Terms of use

CC-BY-NC-ND

Subjects

Permanent link