A contribution to the pathology of the blood : being an account of certain crystalline changes occurring in the haemoglobin after withdrawal from the body, in the subjects of certain diseases, especially those of septic origin / by C.J. Bond.

  • Bond, C. J. (Charles John), 1856-1939.
Date:
[1887]
Catalogue details

Licence: Public Domain Mark

Credit: A contribution to the pathology of the blood : being an account of certain crystalline changes occurring in the haemoglobin after withdrawal from the body, in the subjects of certain diseases, especially those of septic origin / by C.J. Bond. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    THE PATHOLOGY OF THE BLOOD. I make no apology for bringing forward again the well-worn subject of crystallisation of the haemoglobin of the red blood corpuscles; for I think, when viewed in the light about to be described, it is capable of suggesting many useful hints towards the better understanding of the pathology of many diseases, especially those which are associated with the septic processes. If a drop of normal human blood be drawn from the finger, placed on a slide, and covered with a cover glass, no crys- tallisation of the haemoglobin occurs. A ring or cake of dried serum forms around the edge of the cover glass, keep- ing the blood fluid within for many days; and although some changes occur, such as partial exudation of the haemo- globin into the serum, there is no crystallisation of the haemoglobin either in the serum or corpuscles. This is true of the blood of many of the mammals under like conditions —i.e., the blood of the ox, sheep, dog, cat, mole, rabbit, and guinea-pig: and also in the nucleated blood of birds, frogs, toads, and newts. On the other hand, the blood of the apparently healthy mouse, both wild and tame varieties, shows, under the same conditions, well-marked crystallisa- tion of its haemoglobin, both in corpuscles and serum, in from twenty to thirty hours. Between these two extremes